P25445 (P25445)

Overview
Predicted structure (AF):
AF-P25445-F1-model_v4
Uniprot entry:
P25445
Gene:
P25445
Protein length:
335 residues
Mutations found:
6364
Benign based on D2Deep prediction:
4666 out of 6364 mutations
Pathogenic based on D2Deep prediction:
1698 out of 6364 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6364 mutations across 335 unique positions. There are 4666 benign and 1698 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 Q 18 1 19 0.090 0.689 View mutations
27 V 19 0 19 0.008 0.700 View mutations
28 T 19 0 19 0.010 0.748 View mutations
29 D 19 0 19 0.027 0.693 View mutations
30 I 19 0 19 0.011 0.690 View mutations
31 N 19 0 19 0.003 0.771 View mutations
32 S 19 0 19 0.003 0.730 View mutations
33 K 18 1 19 0.098 0.710 View mutations
34 G 19 0 19 0.069 0.660 View mutations
35 L 18 1 19 0.054 0.705 View mutations
36 E 19 0 19 0.016 0.785 View mutations
37 L 18 1 19 0.069 0.653 View mutations
38 R 8 11 19 0.621 0.426 View mutations
39 K 18 1 19 0.107 0.771 View mutations
40 T 17 2 19 0.140 0.692 View mutations
41 V 17 2 19 0.108 0.720 View mutations
42 T 18 1 19 0.042 0.689 View mutations
43 T 18 1 19 0.061 0.727 View mutations
44 V 18 1 19 0.059 0.737 View mutations
45 E 14 5 19 0.298 0.542 View mutations
46 T 18 1 19 0.067 0.621 View mutations
47 Q 19 0 19 0.028 0.678 View mutations
48 N 18 1 19 0.090 0.602 View mutations
49 L 17 2 19 0.179 0.579 View mutations
50 E 2 17 19 0.827 0.379 View mutations