P25445 (P25445)

Overview
Predicted structure (AF):
AF-P25445-F1-model_v4
Uniprot entry:
P25445
Gene:
P25445
Protein length:
335 residues
Mutations found:
6364
Benign based on D2Deep prediction:
4666 out of 6364 mutations
Pathogenic based on D2Deep prediction:
1698 out of 6364 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6364 mutations across 335 unique positions. There are 4666 benign and 1698 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 N 16 3 19 0.241 0.406 View mutations
77 G 11 8 19 0.395 0.497 View mutations
78 D 0 19 19 0.980 0.466 View mutations
79 E 12 7 19 0.474 0.423 View mutations
80 P 0 19 19 0.980 0.529 View mutations
81 D 17 2 19 0.196 0.451 View mutations
82 C 19 0 19 0.013 0.360 View mutations
83 V 18 1 19 0.071 0.371 View mutations
84 P 19 0 19 0.001 0.423 View mutations
85 C 19 0 19 0.016 0.419 View mutations
86 Q 19 0 19 0.001 0.490 View mutations
87 E 0 19 19 0.973 0.580 View mutations
88 G 18 1 19 0.090 0.352 View mutations
89 K 19 0 19 0.000 0.442 View mutations
90 E 19 0 19 0.022 0.333 View mutations
91 Y 19 0 19 0.006 0.259 View mutations
92 T 19 0 19 0.000 0.318 View mutations
93 D 19 0 19 0.011 0.352 View mutations
94 K 19 0 19 0.003 0.362 View mutations
95 A 18 1 19 0.109 0.480 View mutations
96 H 14 5 19 0.405 0.432 View mutations
97 F 19 0 19 0.000 0.439 View mutations
98 S 16 3 19 0.161 0.333 View mutations
99 S 9 10 19 0.530 0.505 View mutations
100 K 13 6 19 0.256 0.456 View mutations