P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 P 0 19 19 0.980 0.432 View mutations
52 L 4 15 19 0.697 0.510 View mutations
53 N 0 19 19 0.972 0.495 View mutations
54 N 18 1 19 0.082 0.395 View mutations
55 F 16 3 19 0.155 0.416 View mutations
56 S 18 1 19 0.086 0.547 View mutations
57 V 1 18 19 0.940 0.512 View mutations
58 A 19 0 19 0.011 0.487 View mutations
59 Q 19 0 19 0.023 0.489 View mutations
60 C 2 17 19 0.899 0.448 View mutations
61 Q 9 10 19 0.538 0.501 View mutations
62 L 4 15 19 0.800 0.419 View mutations
63 M 13 6 19 0.341 0.421 View mutations
64 K 16 3 19 0.202 0.460 View mutations
65 T 19 0 19 0.029 0.452 View mutations
66 E 17 2 19 0.123 0.463 View mutations
67 R 12 7 19 0.374 0.495 View mutations
68 P 1 18 19 0.854 0.598 View mutations
69 R 19 0 19 0.037 0.486 View mutations
70 P 19 0 19 0.002 0.450 View mutations
71 N 15 4 19 0.251 0.493 View mutations
72 T 16 3 19 0.295 0.474 View mutations
73 F 0 19 19 1.000 0.583 View mutations
74 I 6 13 19 0.646 0.513 View mutations
75 I 6 13 19 0.687 0.529 View mutations