P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
451 P 19 0 19 0.000 0.444 View mutations
452 P 13 6 19 0.311 0.486 View mutations
453 D 19 0 19 0.000 0.720 View mutations
454 Q 19 0 19 0.001 0.757 View mutations
455 D 19 0 19 0.001 0.797 View mutations
456 D 17 2 19 0.180 0.728 View mutations
457 S 19 0 19 0.019 0.820 View mutations
458 M 19 0 19 0.024 0.788 View mutations
459 E 19 0 19 0.003 0.758 View mutations
460 C 19 0 19 0.005 0.789 View mutations
461 V 19 0 19 0.001 0.697 View mutations
462 D 19 0 19 0.001 0.774 View mutations
463 S 19 0 19 0.000 0.746 View mutations
464 E 19 0 19 0.000 0.701 View mutations
465 R 15 4 19 0.278 0.694 View mutations
466 R 18 1 19 0.070 0.734 View mutations
467 P 12 7 19 0.376 0.513 View mutations
468 H 19 0 19 0.005 0.667 View mutations
469 F 0 19 19 0.999 0.390 View mutations
470 P 17 2 19 0.148 0.504 View mutations
471 Q 5 14 19 0.745 0.405 View mutations
472 F 15 4 19 0.259 0.435 View mutations
473 S 19 0 19 0.000 0.451 View mutations
474 Y 18 1 19 0.033 0.488 View mutations
475 S 15 4 19 0.277 0.574 View mutations