P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 P 2 17 19 0.877 0.428 View mutations
52 L 4 15 19 0.723 0.517 View mutations
53 N 0 19 19 0.977 0.486 View mutations
54 N 18 1 19 0.061 0.396 View mutations
55 F 13 6 19 0.278 0.429 View mutations
56 S 18 1 19 0.082 0.525 View mutations
57 V 2 17 19 0.893 0.477 View mutations
58 A 19 0 19 0.002 0.468 View mutations
59 E 19 0 19 0.046 0.457 View mutations
60 C 3 16 19 0.856 0.453 View mutations
61 Q 10 9 19 0.416 0.499 View mutations
62 L 4 15 19 0.797 0.434 View mutations
63 M 14 5 19 0.225 0.390 View mutations
64 K 10 9 19 0.434 0.435 View mutations
65 T 19 0 19 0.006 0.414 View mutations
66 E 18 1 19 0.080 0.430 View mutations
67 R 13 6 19 0.417 0.486 View mutations
68 P 1 18 19 0.935 0.588 View mutations
69 R 19 0 19 0.031 0.492 View mutations
70 P 19 0 19 0.001 0.422 View mutations
71 N 17 2 19 0.205 0.487 View mutations
72 T 8 11 19 0.420 0.506 View mutations
73 F 0 19 19 1.000 0.593 View mutations
74 V 10 9 19 0.527 0.499 View mutations
75 I 8 11 19 0.590 0.511 View mutations