P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 Y 7 12 19 0.619 0.442 View mutations
27 F 19 0 19 0.031 0.457 View mutations
28 L 15 4 19 0.252 0.500 View mutations
29 L 19 0 19 0.016 0.406 View mutations
30 K 16 3 19 0.227 0.572 View mutations
31 S 19 0 19 0.002 0.566 View mutations
32 D 12 7 19 0.378 0.431 View mutations
33 G 3 16 19 0.795 0.510 View mutations
34 S 17 2 19 0.148 0.435 View mutations
35 F 3 16 19 0.825 0.531 View mutations
36 I 18 1 19 0.057 0.440 View mutations
37 G 9 10 19 0.457 0.505 View mutations
38 Y 2 17 19 0.898 0.453 View mutations
39 K 2 17 19 0.887 0.505 View mutations
40 E 16 3 19 0.237 0.486 View mutations
41 R 19 0 19 0.107 0.597 View mutations
42 P 19 0 19 0.023 0.635 View mutations
43 E 19 0 19 0.000 0.681 View mutations
44 A 19 0 19 0.003 0.782 View mutations
45 P 17 2 19 0.121 0.738 View mutations
46 D 19 0 19 0.002 0.727 View mutations
47 Q 19 0 19 0.002 0.774 View mutations
48 T 19 0 19 0.012 0.773 View mutations
49 L 19 0 19 0.023 0.733 View mutations
50 P 7 12 19 0.597 0.409 View mutations