P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
401 K 16 3 19 0.224 0.596 View mutations
402 E 19 0 19 0.000 0.561 View mutations
403 V 19 0 19 0.043 0.358 View mutations
404 M 11 8 19 0.442 0.485 View mutations
405 E 19 0 19 0.000 0.642 View mutations
406 H 19 0 19 0.000 0.432 View mutations
407 R 19 0 19 0.000 0.574 View mutations
408 F 0 19 19 0.999 0.424 View mutations
409 F 18 1 19 0.053 0.503 View mutations
410 L 18 1 19 0.061 0.660 View mutations
411 S 19 0 19 0.013 0.632 View mutations
412 I 2 17 19 0.897 0.348 View mutations
413 N 9 10 19 0.476 0.454 View mutations
414 W 17 2 19 0.132 0.587 View mutations
415 Q 19 0 19 0.000 0.678 View mutations
416 D 3 16 19 0.853 0.297 View mutations
417 V 8 11 19 0.525 0.434 View mutations
418 V 19 0 19 0.014 0.619 View mutations
419 Q 19 0 19 0.001 0.715 View mutations
420 K 1 18 19 0.942 0.375 View mutations
421 K 17 2 19 0.107 0.571 View mutations
422 L 19 0 19 0.017 0.592 View mutations
423 L 19 0 19 0.027 0.663 View mutations
424 P 15 4 19 0.249 0.409 View mutations
425 P 19 0 19 0.003 0.404 View mutations