P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 R 4 15 19 0.805 0.557 View mutations
77 C 10 9 19 0.457 0.499 View mutations
78 L 0 19 19 0.993 0.532 View mutations
79 Q 7 12 19 0.642 0.526 View mutations
80 W 1 18 19 0.950 0.573 View mutations
81 T 4 15 19 0.787 0.582 View mutations
82 T 5 14 19 0.707 0.537 View mutations
83 V 6 13 19 0.681 0.524 View mutations
84 I 14 5 19 0.283 0.454 View mutations
85 E 0 19 19 0.938 0.630 View mutations
86 R 5 14 19 0.580 0.515 View mutations
87 T 4 15 19 0.761 0.455 View mutations
88 F 8 11 19 0.608 0.517 View mutations
89 H 19 0 19 0.001 0.490 View mutations
90 V 19 0 19 0.000 0.438 View mutations
91 D 19 0 19 0.002 0.474 View mutations
92 S 19 0 19 0.000 0.521 View mutations
93 P 19 0 19 0.014 0.518 View mutations
94 D 19 0 19 0.001 0.507 View mutations
95 E 17 2 19 0.210 0.438 View mutations
96 R 0 19 19 0.955 0.506 View mutations
97 E 19 0 19 0.015 0.489 View mutations
98 E 19 0 19 0.066 0.501 View mutations
99 W 4 15 19 0.774 0.560 View mutations
100 M 4 15 19 0.805 0.436 View mutations