P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 Q 19 0 19 0.029 0.855 View mutations
77 E 19 0 19 0.031 0.801 View mutations
78 Q 15 4 19 0.229 0.663 View mutations
79 V 16 3 19 0.194 0.670 View mutations
80 A 19 0 19 0.071 0.805 View mutations
81 D 17 2 19 0.173 0.675 View mutations
82 I 17 2 19 0.074 0.687 View mutations
83 D 18 1 19 0.108 0.669 View mutations
84 G 19 0 19 0.005 0.775 View mutations
85 Q 19 0 19 0.008 0.679 View mutations
86 Y 19 0 19 0.000 0.585 View mutations
87 A 15 4 19 0.231 0.559 View mutations
88 M 19 0 19 0.003 0.678 View mutations
89 T 19 0 19 0.000 0.517 View mutations
90 R 19 0 19 0.002 0.509 View mutations
91 A 16 3 19 0.171 0.452 View mutations
92 Q 19 0 19 0.000 0.503 View mutations
93 R 3 16 19 0.770 0.432 View mutations
94 V 19 0 19 0.020 0.401 View mutations
95 R 8 11 19 0.641 0.436 View mutations
96 A 11 8 19 0.459 0.418 View mutations
97 A 19 0 19 0.025 0.370 View mutations
98 M 17 2 19 0.144 0.495 View mutations
99 F 6 13 19 0.665 0.452 View mutations
100 P 6 13 19 0.621 0.523 View mutations