P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
701 G 19 0 19 0.001 0.898 View mutations
702 A 19 0 19 0.001 0.949 View mutations
703 Q 19 0 19 0.002 0.924 View mutations
704 G 17 2 19 0.204 0.843 View mutations
705 E 19 0 19 0.035 0.929 View mutations
706 P 19 0 19 0.000 0.895 View mutations
707 L 15 4 19 0.224 0.732 View mutations
708 G 19 0 19 0.015 0.923 View mutations
709 Y 19 0 19 0.001 0.934 View mutations
710 R 19 0 19 0.001 0.973 View mutations
711 Q 17 2 19 0.093 0.865 View mutations
712 D 19 0 19 0.006 0.945 View mutations
713 D 19 0 19 0.001 0.988 View mutations
714 P 19 0 19 0.002 0.948 View mutations
715 S 19 0 19 0.018 0.965 View mutations
716 Y 19 0 19 0.001 0.920 View mutations
717 R 19 0 19 0.000 0.962 View mutations
718 S 19 0 19 0.070 0.926 View mutations
719 F 19 0 19 0.012 0.910 View mutations
720 H 19 0 19 0.031 0.945 View mutations
721 S 19 0 19 0.042 0.913 View mutations
722 G 12 7 19 0.416 0.593 View mutations
723 G 19 0 19 0.010 0.966 View mutations
724 Y 19 0 19 0.002 0.917 View mutations
725 G 19 0 19 0.004 0.938 View mutations