P42772 (CDKN2B)

Overview
Predicted structure (AF):
AF-P42772-F1-model_v4
Uniprot entry:
P42772
Gene:
CDKN2B
Protein length:
138 residues
Mutations found:
2621
Benign based on D2Deep prediction:
1462 out of 2621 mutations
Pathogenic based on D2Deep prediction:
1159 out of 2621 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2621 mutations across 138 unique positions. There are 1462 benign and 1159 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 L 15 4 19 0.208 0.566 View mutations
27 V 19 0 19 0.011 0.704 View mutations
28 E 19 0 19 0.000 0.777 View mutations
29 K 12 7 19 0.358 0.550 View mutations
30 V 2 17 19 0.883 0.435 View mutations
31 R 18 1 19 0.053 0.713 View mutations
32 Q 19 0 19 0.005 0.707 View mutations
33 L 4 15 19 0.784 0.389 View mutations
34 L 19 0 19 0.068 0.467 View mutations
35 E 17 2 19 0.146 0.578 View mutations
36 A 19 0 19 0.030 0.618 View mutations
37 G 19 0 19 0.076 0.422 View mutations
38 A 5 14 19 0.723 0.417 View mutations
39 D 7 12 19 0.689 0.425 View mutations
40 P 12 7 19 0.385 0.499 View mutations
41 N 17 2 19 0.155 0.416 View mutations
42 G 19 0 19 0.025 0.497 View mutations
43 V 19 0 19 0.001 0.365 View mutations
44 N 13 6 19 0.392 0.430 View mutations
45 R 7 12 19 0.599 0.420 View mutations
46 F 12 7 19 0.394 0.455 View mutations
47 G 2 17 19 0.851 0.609 View mutations
48 R 0 19 19 0.968 0.526 View mutations
49 R 10 9 19 0.490 0.424 View mutations
50 A 1 18 19 0.948 0.562 View mutations