P42773 (CDKN2C)

Overview
Predicted structure (AF):
AF-P42773-F1-model_v4
Uniprot entry:
P42773
Gene:
CDKN2C
Protein length:
168 residues
Mutations found:
3191
Benign based on D2Deep prediction:
1762 out of 3191 mutations
Pathogenic based on D2Deep prediction:
1429 out of 3191 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3191 mutations across 168 unique positions. There are 1762 benign and 1429 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 D 0 19 19 1.000 0.689 View mutations
77 A 3 16 19 0.849 0.700 View mutations
78 A 0 19 19 0.998 0.934 View mutations
79 R 0 19 19 0.954 0.796 View mutations
80 A 2 17 19 0.856 0.791 View mutations
81 G 0 19 19 1.000 1.000 View mutations
82 F 0 19 19 0.999 0.771 View mutations
83 L 5 14 19 0.752 0.453 View mutations
84 D 1 18 19 0.952 0.731 View mutations
85 T 0 19 19 1.000 0.806 View mutations
86 L 8 11 19 0.513 0.503 View mutations
87 Q 18 1 19 0.083 0.497 View mutations
88 T 12 7 19 0.381 0.480 View mutations
89 L 3 16 19 0.775 0.673 View mutations
90 L 14 5 19 0.312 0.397 View mutations
91 E 19 0 19 0.006 0.444 View mutations
92 F 19 0 19 0.024 0.500 View mutations
93 Q 19 0 19 0.004 0.351 View mutations
94 A 19 0 19 0.040 0.262 View mutations
95 D 17 2 19 0.220 0.367 View mutations
96 V 11 8 19 0.507 0.473 View mutations
97 N 18 1 19 0.093 0.389 View mutations
98 I 19 0 19 0.042 0.429 View mutations
99 E 2 17 19 0.844 0.577 View mutations
100 D 7 12 19 0.624 0.579 View mutations