P46109 (P46109)

Overview
Predicted structure (AF):
AF-P46109-F1-model_v4
Uniprot entry:
P46109
Gene:
P46109
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
2311 out of 5756 mutations
Pathogenic based on D2Deep prediction:
3445 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5756 mutations across 303 unique positions. There are 2311 benign and 3445 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 P 17 2 19 0.126 0.827 View mutations
202 E 19 0 19 0.012 0.910 View mutations
203 P 19 0 19 0.004 0.922 View mutations
204 A 19 0 19 0.001 0.929 View mutations
205 H 18 1 19 0.059 0.870 View mutations
206 A 16 3 19 0.255 0.781 View mutations
207 Y 18 1 19 0.085 0.866 View mutations
208 A 19 0 19 0.030 0.893 View mutations
209 Q 19 0 19 0.125 0.892 View mutations
210 P 19 0 19 0.010 0.888 View mutations
211 Q 19 0 19 0.012 0.948 View mutations
212 T 17 2 19 0.179 0.861 View mutations
213 T 19 0 19 0.016 0.965 View mutations
214 T 18 1 19 0.107 0.884 View mutations
215 P 19 0 19 0.025 0.959 View mutations
216 L 15 4 19 0.269 0.749 View mutations
217 P 19 0 19 0.030 1.000 View mutations
218 A 18 1 19 0.062 0.941 View mutations
219 V 19 0 19 0.030 0.945 View mutations
220 S 17 2 19 0.106 0.841 View mutations
221 G 19 0 19 0.003 0.933 View mutations
222 S 19 0 19 0.025 0.885 View mutations
223 P 16 3 19 0.162 0.748 View mutations
224 G 19 0 19 0.085 0.814 View mutations
225 A 14 5 19 0.298 0.627 View mutations