P46109 (P46109)

Overview
Predicted structure (AF):
AF-P46109-F1-model_v4
Uniprot entry:
P46109
Gene:
P46109
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
2311 out of 5756 mutations
Pathogenic based on D2Deep prediction:
3445 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5756 mutations across 303 unique positions. There are 2311 benign and 3445 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 P 19 0 19 0.006 0.435 View mutations
102 A 19 0 19 0.001 0.403 View mutations
103 P 19 0 19 0.009 0.571 View mutations
104 R 6 13 19 0.677 0.410 View mutations
105 Y 4 15 19 0.777 0.332 View mutations
106 P 17 2 19 0.116 0.686 View mutations
107 S 18 1 19 0.035 0.772 View mutations
108 P 19 0 19 0.026 0.765 View mutations
109 P 19 0 19 0.005 0.802 View mutations
110 M 19 0 19 0.001 0.805 View mutations
111 G 19 0 19 0.003 0.814 View mutations
112 S 19 0 19 0.001 0.819 View mutations
113 V 19 0 19 0.006 0.831 View mutations
114 S 19 0 19 0.012 0.877 View mutations
115 A 19 0 19 0.012 0.844 View mutations
116 P 19 0 19 0.022 0.852 View mutations
117 N 19 0 19 0.007 0.794 View mutations
118 L 19 0 19 0.013 0.801 View mutations
119 P 19 0 19 0.011 0.792 View mutations
120 T 19 0 19 0.021 0.811 View mutations
121 A 19 0 19 0.035 0.786 View mutations
122 E 19 0 19 0.010 0.767 View mutations
123 D 7 12 19 0.642 0.403 View mutations
124 N 17 2 19 0.200 0.628 View mutations
125 L 9 10 19 0.469 0.453 View mutations