P48023 (FASLG)

Overview
Predicted structure (AF):
AF-P48023-F1-model_v4
Uniprot entry:
P48023
Gene:
FASLG
Protein length:
281 residues
Mutations found:
5338
Benign based on D2Deep prediction:
2681 out of 5338 mutations
Pathogenic based on D2Deep prediction:
2657 out of 5338 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5338 mutations across 281 unique positions. There are 2681 benign and 2657 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 Y 9 10 19 0.561 0.509 View mutations
177 K 14 5 19 0.250 0.392 View mutations
178 K 14 5 19 0.283 0.421 View mutations
179 G 18 1 19 0.206 0.447 View mutations
180 G 11 8 19 0.422 0.415 View mutations
181 L 4 15 19 0.827 0.609 View mutations
182 V 4 15 19 0.732 0.534 View mutations
183 I 3 16 19 0.865 0.610 View mutations
184 N 7 12 19 0.639 0.520 View mutations
185 E 19 0 19 0.053 0.349 View mutations
186 T 9 10 19 0.534 0.507 View mutations
187 G 0 19 19 0.989 0.834 View mutations
188 L 1 18 19 0.925 0.664 View mutations
189 Y 0 19 19 0.994 0.839 View mutations
190 F 0 19 19 0.999 0.827 View mutations
191 V 3 16 19 0.853 0.708 View mutations
192 Y 1 18 19 0.954 0.809 View mutations
193 S 2 17 19 0.914 0.802 View mutations
194 K 2 17 19 0.854 0.706 View mutations
195 V 3 16 19 0.866 0.758 View mutations
196 Y 15 4 19 0.220 0.346 View mutations
197 F 2 17 19 0.882 0.761 View mutations
198 R 7 12 19 0.624 0.548 View mutations
199 G 0 19 19 0.941 0.642 View mutations
200 Q 9 10 19 0.543 0.504 View mutations