P48023 (FASLG)

Overview
Predicted structure (AF):
AF-P48023-F1-model_v4
Uniprot entry:
P48023
Gene:
FASLG
Protein length:
281 residues
Mutations found:
5338
Benign based on D2Deep prediction:
2681 out of 5338 mutations
Pathogenic based on D2Deep prediction:
2657 out of 5338 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5338 mutations across 281 unique positions. There are 2681 benign and 2657 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 M 16 3 19 0.131 0.476 View mutations
102 F 17 2 19 0.090 0.425 View mutations
103 Q 4 15 19 0.638 0.559 View mutations
104 L 2 17 19 0.889 0.584 View mutations
105 F 2 17 19 0.856 0.588 View mutations
106 H 5 14 19 0.678 0.527 View mutations
107 L 4 15 19 0.732 0.573 View mutations
108 Q 1 18 19 0.892 0.601 View mutations
109 K 18 1 19 0.053 0.452 View mutations
110 E 10 9 19 0.403 0.496 View mutations
111 L 14 5 19 0.283 0.431 View mutations
112 A 8 11 19 0.468 0.516 View mutations
113 E 18 1 19 0.028 0.366 View mutations
114 L 19 0 19 0.054 0.468 View mutations
115 R 18 1 19 0.098 0.405 View mutations
116 E 19 0 19 0.039 0.460 View mutations
117 S 14 5 19 0.316 0.501 View mutations
118 T 18 1 19 0.074 0.637 View mutations
119 S 19 0 19 0.008 0.702 View mutations
120 Q 19 0 19 0.003 0.689 View mutations
121 M 18 1 19 0.080 0.681 View mutations
122 H 17 2 19 0.128 0.686 View mutations
123 T 14 5 19 0.285 0.598 View mutations
124 A 15 4 19 0.231 0.606 View mutations
125 S 11 8 19 0.433 0.477 View mutations