P50148 (GNAQ)

Overview
Predicted structure (AF):
AF-P50148-F1-model_v4
Uniprot entry:
P50148
Gene:
GNAQ
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
4080 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2740 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 4080 benign and 2740 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 S 0 19 19 0.968 0.692 View mutations
252 K 10 9 19 0.483 0.422 View mutations
253 A 2 17 19 0.882 0.559 View mutations
254 L 17 2 19 0.098 0.287 View mutations
255 F 10 9 19 0.511 0.490 View mutations
256 R 6 13 19 0.651 0.406 View mutations
257 T 0 19 19 0.973 0.562 View mutations
258 I 9 10 19 0.525 0.504 View mutations
259 I 16 3 19 0.192 0.484 View mutations
260 T 19 0 19 0.002 0.465 View mutations
261 Y 6 13 19 0.723 0.426 View mutations
262 P 4 15 19 0.749 0.443 View mutations
263 W 9 10 19 0.510 0.502 View mutations
264 F 0 19 19 0.988 0.688 View mutations
265 Q 19 0 19 0.007 0.463 View mutations
266 N 19 0 19 0.000 0.471 View mutations
267 S 2 17 19 0.913 0.564 View mutations
268 S 12 7 19 0.414 0.458 View mutations
269 V 2 17 19 0.876 0.544 View mutations
270 I 0 19 19 0.999 0.823 View mutations
271 L 0 19 19 1.000 0.841 View mutations
272 F 7 12 19 0.571 0.610 View mutations
273 L 6 13 19 0.673 0.595 View mutations
274 N 0 19 19 0.997 0.915 View mutations
275 K 18 1 19 0.056 0.227 View mutations