P50148 (GNAQ)

Overview
Predicted structure (AF):
AF-P50148-F1-model_v4
Uniprot entry:
P50148
Gene:
GNAQ
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
4080 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2740 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 4080 benign and 2740 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 F 5 14 19 0.738 0.506 View mutations
202 R 11 8 19 0.378 0.490 View mutations
203 M 18 1 19 0.042 0.384 View mutations
204 V 19 0 19 0.001 0.260 View mutations
205 D 4 15 19 0.765 0.789 View mutations
206 V 0 19 19 1.000 0.927 View mutations
207 G 0 19 19 1.000 0.871 View mutations
208 G 0 19 19 0.981 0.917 View mutations
209 Q 0 19 19 0.997 0.895 View mutations
210 R 17 2 19 0.100 0.308 View mutations
211 S 1 18 19 0.922 0.739 View mutations
212 E 0 19 19 1.000 0.890 View mutations
213 R 0 19 19 1.000 0.904 View mutations
214 R 1 18 19 0.953 0.786 View mutations
215 K 0 19 19 1.000 0.902 View mutations
216 W 0 19 19 1.000 0.980 View mutations
217 I 0 19 19 0.999 0.864 View mutations
218 H 0 19 19 0.995 0.846 View mutations
219 C 4 15 19 0.738 0.666 View mutations
220 F 19 0 19 0.021 0.073 View mutations
221 E 19 0 19 0.051 0.262 View mutations
222 N 14 5 19 0.256 0.434 View mutations
223 V 19 0 19 0.001 0.304 View mutations
224 T 9 10 19 0.507 0.508 View mutations
225 S 3 16 19 0.800 0.555 View mutations