P50148 (GNAQ)

Overview
Predicted structure (AF):
AF-P50148-F1-model_v4
Uniprot entry:
P50148
Gene:
GNAQ
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
4080 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2740 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 4080 benign and 2740 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 I 3 16 19 0.867 0.646 View mutations
227 M 19 0 19 0.014 0.276 View mutations
228 F 0 19 19 0.976 0.745 View mutations
229 L 0 19 19 1.000 0.673 View mutations
230 V 1 18 19 0.946 0.630 View mutations
231 A 1 18 19 0.933 0.674 View mutations
232 L 1 18 19 0.955 0.671 View mutations
233 S 0 19 19 1.000 0.721 View mutations
234 E 0 19 19 1.000 0.719 View mutations
235 Y 5 14 19 0.628 0.637 View mutations
236 D 11 8 19 0.449 0.473 View mutations
237 Q 4 15 19 0.807 0.542 View mutations
238 V 3 16 19 0.831 0.519 View mutations
239 L 0 19 19 1.000 0.607 View mutations
240 V 17 2 19 0.082 0.440 View mutations
241 E 19 0 19 0.063 0.441 View mutations
242 S 15 4 19 0.178 0.510 View mutations
243 D 19 0 19 0.009 0.509 View mutations
244 N 19 0 19 0.000 0.519 View mutations
245 E 13 6 19 0.367 0.496 View mutations
246 N 4 15 19 0.806 0.537 View mutations
247 R 13 6 19 0.321 0.426 View mutations
248 M 1 18 19 0.950 0.575 View mutations
249 E 1 18 19 0.966 0.420 View mutations
250 E 0 19 19 0.990 0.743 View mutations