P58012 (P58012)

Overview
Predicted structure (AF):
AF-P58012-F1-model_v4
Uniprot entry:
P58012
Gene:
P58012
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4360 out of 7143 mutations
Pathogenic based on D2Deep prediction:
2783 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4360 benign and 2783 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 S 10 9 19 0.439 0.477 View mutations
102 I 17 2 19 0.129 0.171 View mutations
103 R 2 17 19 0.762 0.854 View mutations
104 H 13 6 19 0.338 0.346 View mutations
105 N 11 8 19 0.472 0.429 View mutations
106 L 4 15 19 0.722 0.782 View mutations
107 S 9 10 19 0.545 0.525 View mutations
108 L 9 10 19 0.473 0.526 View mutations
109 N 1 18 19 0.851 0.946 View mutations
110 E 1 18 19 0.754 0.901 View mutations
111 C 11 8 19 0.434 0.431 View mutations
112 F 1 18 19 0.896 0.947 View mutations
113 I 8 11 19 0.503 0.565 View mutations
114 K 1 18 19 0.922 0.870 View mutations
115 V 3 16 19 0.798 0.838 View mutations
116 P 3 16 19 0.812 0.807 View mutations
117 R 1 18 19 0.943 0.841 View mutations
118 E 0 19 19 0.978 0.924 View mutations
119 G 0 19 19 0.948 0.926 View mutations
120 G 0 19 19 0.955 0.926 View mutations
121 G 0 19 19 0.986 0.938 View mutations
122 E 0 19 19 0.999 0.892 View mutations
123 R 0 19 19 0.999 0.853 View mutations
124 K 0 19 19 0.961 0.915 View mutations
125 G 0 19 19 0.991 0.947 View mutations