P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
376 V 16 3 19 0.257 0.229 View mutations
377 D 5 14 19 0.672 0.699 View mutations
378 A 0 19 19 1.000 0.981 View mutations
379 S 2 17 19 0.928 0.887 View mutations
380 Y 0 19 19 1.000 0.942 View mutations
381 Y 0 19 19 1.000 0.946 View mutations
382 G 0 19 19 1.000 0.961 View mutations
383 G 0 19 19 1.000 0.913 View mutations
384 R 13 6 19 0.368 0.378 View mutations
385 G 0 19 19 1.000 0.937 View mutations
386 V 3 16 19 0.851 0.756 View mutations
387 G 0 19 19 0.989 0.913 View mutations
388 G 10 9 19 0.532 0.475 View mutations
389 I 2 17 19 0.872 0.806 View mutations
390 K 11 8 19 0.407 0.459 View mutations
391 R 3 16 19 0.882 0.791 View mutations
392 M 5 14 19 0.717 0.699 View mutations
393 E 1 18 19 0.961 0.915 View mutations
394 V 1 18 19 0.921 0.850 View mutations
395 R 19 0 19 0.000 0.191 View mutations
396 W 1 18 19 0.964 0.796 View mutations
397 G 1 18 19 0.946 0.850 View mutations
398 D 4 15 19 0.762 0.662 View mutations
399 K 14 5 19 0.244 0.366 View mutations
400 G 0 19 19 0.970 1.000 View mutations