P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 L 19 0 19 0.031 0.343 View mutations
152 D 15 4 19 0.247 0.443 View mutations
153 G 19 0 19 0.021 0.356 View mutations
154 L 19 0 19 0.003 0.434 View mutations
155 V 10 9 19 0.542 0.500 View mutations
156 P 14 5 19 0.284 0.407 View mutations
157 S 19 0 19 0.004 0.439 View mutations
158 Y 17 2 19 0.177 0.393 View mutations
159 A 6 13 19 0.669 0.537 View mutations
160 E 17 2 19 0.091 0.411 View mutations
161 K 17 2 19 0.102 0.471 View mutations
162 E 3 16 19 0.860 0.446 View mutations
163 A 0 19 19 0.970 0.669 View mutations
164 K 16 3 19 0.170 0.446 View mutations
165 I 18 1 19 0.091 0.461 View mutations
166 S 2 17 19 0.901 0.581 View mutations
167 R 18 1 19 0.157 0.266 View mutations
168 S 17 2 19 0.156 0.376 View mutations
169 L 18 1 19 0.092 0.492 View mutations
170 G 7 12 19 0.607 0.589 View mutations
171 A 0 19 19 1.000 0.814 View mutations
172 S 14 5 19 0.229 0.417 View mutations
173 V 6 13 19 0.698 0.624 View mutations
174 Y 1 18 19 0.934 0.859 View mutations
175 C 0 19 19 1.000 0.918 View mutations