P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 V 0 19 19 0.999 0.929 View mutations
177 G 0 19 19 1.000 0.980 View mutations
178 V 1 18 19 0.933 0.829 View mutations
179 L 9 10 19 0.537 0.512 View mutations
180 D 2 17 19 0.898 0.714 View mutations
181 F 1 18 19 0.913 0.778 View mutations
182 E 17 2 19 0.097 0.408 View mutations
183 Q 17 2 19 0.125 0.436 View mutations
184 A 15 4 19 0.227 0.424 View mutations
185 Q 19 0 19 0.044 0.179 View mutations
186 L 18 1 19 0.067 0.202 View mutations
187 E 16 3 19 0.171 0.448 View mutations
188 R 19 0 19 0.015 0.498 View mutations
189 I 0 19 19 0.951 0.817 View mutations
190 A 0 19 19 0.973 0.756 View mutations
191 D 2 17 19 0.903 0.613 View mutations
192 S 15 4 19 0.220 0.465 View mutations
193 K 18 1 19 0.084 0.444 View mutations
194 E 12 7 19 0.368 0.475 View mutations
195 Q 15 4 19 0.179 0.394 View mutations
196 V 18 1 19 0.083 0.184 View mutations
197 F 13 6 19 0.448 0.386 View mutations
198 P 0 19 19 0.997 0.803 View mutations
199 V 3 16 19 0.808 0.740 View mutations
200 K 8 11 19 0.562 0.515 View mutations