P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 G 3 16 19 0.794 0.651 View mutations
202 G 17 2 19 0.164 0.254 View mutations
203 F 19 0 19 0.000 0.167 View mutations
204 Q 19 0 19 0.000 0.427 View mutations
205 A 0 19 19 0.971 0.828 View mutations
206 L 1 18 19 0.958 0.842 View mutations
207 K 6 13 19 0.626 0.557 View mutations
208 G 10 9 19 0.482 0.488 View mutations
209 I 3 16 19 0.844 0.701 View mutations
210 I 14 5 19 0.248 0.339 View mutations
211 N 9 10 19 0.556 0.509 View mutations
212 S 0 19 19 0.999 0.721 View mutations
213 I 1 18 19 0.961 0.803 View mutations
214 L 1 18 19 0.940 0.756 View mutations
215 A 14 5 19 0.298 0.457 View mutations
216 Q 2 17 19 0.895 0.630 View mutations
217 S 2 17 19 0.855 0.705 View mutations
218 C 0 19 19 1.000 0.756 View mutations
219 T 18 1 19 0.064 0.343 View mutations
220 E 19 0 19 0.002 0.342 View mutations
221 I 19 0 19 0.015 0.328 View mutations
222 L 11 8 19 0.446 0.487 View mutations
223 E 19 0 19 0.001 0.482 View mutations
224 L 6 13 19 0.627 0.579 View mutations
225 Q 12 7 19 0.341 0.469 View mutations