P61073 (CXCR4)

Overview
Predicted structure (AF):
AF-P61073-F1-model_v4
Uniprot entry:
P61073
Gene:
CXCR4
Protein length:
352 residues
Mutations found:
6687
Benign based on D2Deep prediction:
2592 out of 6687 mutations
Pathogenic based on D2Deep prediction:
4095 out of 6687 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6687 mutations across 352 unique positions. There are 2592 benign and 4095 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 L 1 18 19 0.925 0.835 View mutations
302 Y 0 19 19 0.948 0.927 View mutations
303 A 0 19 19 1.000 0.883 View mutations
304 F 0 19 19 1.000 0.837 View mutations
305 L 13 6 19 0.303 0.378 View mutations
306 G 0 19 19 1.000 0.771 View mutations
307 A 6 13 19 0.690 0.552 View mutations
308 K 9 10 19 0.590 0.504 View mutations
309 F 0 19 19 0.990 0.691 View mutations
310 K 1 18 19 0.954 0.554 View mutations
311 T 11 8 19 0.362 0.423 View mutations
312 S 19 0 19 0.001 0.364 View mutations
313 A 9 10 19 0.570 0.504 View mutations
314 Q 6 13 19 0.693 0.434 View mutations
315 H 16 3 19 0.241 0.424 View mutations
316 A 13 6 19 0.329 0.436 View mutations
317 L 9 10 19 0.515 0.437 View mutations
318 T 19 0 19 0.014 0.624 View mutations
319 S 13 6 19 0.283 0.543 View mutations
320 V 17 2 19 0.124 0.629 View mutations
321 S 5 14 19 0.698 0.391 View mutations
322 R 6 13 19 0.702 0.403 View mutations
323 G 17 2 19 0.117 0.528 View mutations
324 S 1 18 19 0.911 0.363 View mutations
325 S 2 17 19 0.876 0.382 View mutations