P61073 (CXCR4)

Overview
Predicted structure (AF):
AF-P61073-F1-model_v4
Uniprot entry:
P61073
Gene:
CXCR4
Protein length:
352 residues
Mutations found:
6687
Benign based on D2Deep prediction:
2592 out of 6687 mutations
Pathogenic based on D2Deep prediction:
4095 out of 6687 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6687 mutations across 352 unique positions. There are 2592 benign and 4095 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 F 3 16 19 0.839 0.400 View mutations
277 E 13 6 19 0.326 0.481 View mutations
278 N 19 0 19 0.008 0.588 View mutations
279 T 15 4 19 0.238 0.522 View mutations
280 V 1 18 19 0.922 0.465 View mutations
281 H 6 13 19 0.643 0.420 View mutations
282 K 17 2 19 0.133 0.478 View mutations
283 W 1 18 19 0.941 0.428 View mutations
284 I 0 19 19 0.987 0.517 View mutations
285 S 13 6 19 0.331 0.452 View mutations
286 I 11 8 19 0.442 0.494 View mutations
287 T 3 16 19 0.835 0.555 View mutations
288 E 0 19 19 1.000 0.672 View mutations
289 A 11 8 19 0.428 0.491 View mutations
290 L 2 17 19 0.912 0.627 View mutations
291 A 0 19 19 1.000 0.743 View mutations
292 F 1 18 19 0.938 0.700 View mutations
293 F 7 12 19 0.649 0.558 View mutations
294 H 0 19 19 1.000 0.809 View mutations
295 C 0 19 19 0.998 0.836 View mutations
296 C 1 18 19 0.946 0.854 View mutations
297 L 0 19 19 1.000 0.958 View mutations
298 N 0 19 19 1.000 0.960 View mutations
299 P 0 19 19 1.000 1.000 View mutations
300 I 0 19 19 1.000 0.938 View mutations