P61073 (CXCR4)

Overview
Predicted structure (AF):
AF-P61073-F1-model_v4
Uniprot entry:
P61073
Gene:
CXCR4
Protein length:
352 residues
Mutations found:
6687
Benign based on D2Deep prediction:
2592 out of 6687 mutations
Pathogenic based on D2Deep prediction:
4095 out of 6687 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6687 mutations across 352 unique positions. There are 2592 benign and 4095 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 N 19 0 19 0.007 0.486 View mutations
102 W 9 10 19 0.491 0.502 View mutations
103 Y 13 6 19 0.355 0.443 View mutations
104 F 0 19 19 1.000 0.531 View mutations
105 G 0 19 19 0.988 0.499 View mutations
106 N 19 0 19 0.021 0.572 View mutations
107 F 19 0 19 0.001 0.517 View mutations
108 L 4 15 19 0.788 0.413 View mutations
109 C 2 17 19 0.875 0.556 View mutations
110 K 18 1 19 0.052 0.437 View mutations
111 A 9 10 19 0.543 0.438 View mutations
112 V 2 17 19 0.848 0.588 View mutations
113 H 17 2 19 0.135 0.444 View mutations
114 V 17 2 19 0.145 0.393 View mutations
115 I 0 19 19 0.963 0.621 View mutations
116 Y 4 15 19 0.740 0.620 View mutations
117 T 0 19 19 1.000 0.730 View mutations
118 V 3 16 19 0.828 0.619 View mutations
119 N 0 19 19 1.000 0.777 View mutations
120 L 0 19 19 1.000 0.853 View mutations
121 Y 0 19 19 1.000 0.836 View mutations
122 S 0 19 19 0.974 0.829 View mutations
123 S 0 19 19 1.000 0.956 View mutations
124 V 0 19 19 1.000 0.974 View mutations
125 L 0 19 19 1.000 0.943 View mutations