P61586 (RHOA)

Overview
Predicted structure (AF):
AF-P61586-F1-model_v4
Uniprot entry:
P61586
Gene:
RHOA
Protein length:
193 residues
Mutations found:
3666
Benign based on D2Deep prediction:
2470 out of 3666 mutations
Pathogenic based on D2Deep prediction:
1196 out of 3666 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3666 mutations across 193 unique positions. There are 2470 benign and 1196 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 K 7 12 19 0.637 0.407 View mutations
52 Q 19 0 19 0.026 0.774 View mutations
53 V 0 19 19 0.988 0.329 View mutations
54 E 19 0 19 0.025 0.640 View mutations
55 L 19 0 19 0.000 0.367 View mutations
56 A 14 5 19 0.293 0.519 View mutations
57 L 0 19 19 1.000 0.708 View mutations
58 W 13 6 19 0.313 0.471 View mutations
59 D 7 12 19 0.667 0.594 View mutations
60 T 7 12 19 0.661 0.632 View mutations
61 A 0 19 19 1.000 0.943 View mutations
62 G 0 19 19 1.000 0.966 View mutations
63 Q 17 2 19 0.255 0.323 View mutations
64 E 8 11 19 0.540 0.538 View mutations
65 D 7 12 19 0.660 0.529 View mutations
66 Y 0 19 19 0.988 0.710 View mutations
67 D 0 19 19 0.981 0.715 View mutations
68 R 0 19 19 0.991 0.709 View mutations
69 L 19 0 19 0.023 0.248 View mutations
70 R 18 1 19 0.149 0.252 View mutations
71 P 0 19 19 0.976 0.658 View mutations
72 L 1 18 19 0.890 0.677 View mutations
73 S 0 19 19 0.998 0.573 View mutations
74 Y 3 16 19 0.798 0.582 View mutations
75 P 3 16 19 0.756 0.561 View mutations