P61586 (RHOA)

Overview
Predicted structure (AF):
AF-P61586-F1-model_v4
Uniprot entry:
P61586
Gene:
RHOA
Protein length:
193 residues
Mutations found:
3666
Benign based on D2Deep prediction:
2470 out of 3666 mutations
Pathogenic based on D2Deep prediction:
1196 out of 3666 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3666 mutations across 193 unique positions. There are 2470 benign and 1196 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 S 15 4 19 0.259 0.646 View mutations
27 K 17 2 19 0.175 0.790 View mutations
28 D 10 9 19 0.425 0.481 View mutations
29 Q 16 3 19 0.233 0.677 View mutations
30 F 2 17 19 0.853 0.315 View mutations
31 P 17 2 19 0.137 0.522 View mutations
32 E 19 0 19 0.001 0.630 View mutations
33 V 10 9 19 0.478 0.476 View mutations
34 Y 19 0 19 0.036 0.558 View mutations
35 V 10 9 19 0.467 0.463 View mutations
36 P 18 1 19 0.115 0.406 View mutations
37 T 19 0 19 0.010 0.446 View mutations
38 V 1 18 19 0.948 0.436 View mutations
39 F 0 19 19 0.999 0.401 View mutations
40 E 2 17 19 0.871 0.326 View mutations
41 N 2 17 19 0.855 0.345 View mutations
42 Y 11 8 19 0.425 0.492 View mutations
43 V 19 0 19 0.001 0.672 View mutations
44 A 11 8 19 0.428 0.462 View mutations
45 D 4 15 19 0.749 0.339 View mutations
46 I 14 5 19 0.228 0.510 View mutations
47 E 19 0 19 0.000 0.677 View mutations
48 V 17 2 19 0.127 0.540 View mutations
49 D 13 6 19 0.400 0.506 View mutations
50 G 2 17 19 0.832 0.387 View mutations