P61586 (RHOA)

Overview
Predicted structure (AF):
AF-P61586-F1-model_v4
Uniprot entry:
P61586
Gene:
RHOA
Protein length:
193 residues
Mutations found:
3666
Benign based on D2Deep prediction:
2470 out of 3666 mutations
Pathogenic based on D2Deep prediction:
1196 out of 3666 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3666 mutations across 193 unique positions. There are 2470 benign and 1196 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 D 5 14 19 0.750 0.453 View mutations
77 T 9 10 19 0.516 0.437 View mutations
78 D 1 18 19 0.966 0.504 View mutations
79 V 1 18 19 0.911 0.475 View mutations
80 I 1 18 19 0.926 0.425 View mutations
81 L 1 18 19 0.949 0.531 View mutations
82 M 3 16 19 0.849 0.474 View mutations
83 C 0 19 19 0.977 0.465 View mutations
84 F 15 4 19 0.295 0.465 View mutations
85 S 6 13 19 0.589 0.444 View mutations
86 I 16 3 19 0.155 0.479 View mutations
87 D 10 9 19 0.470 0.444 View mutations
88 S 18 1 19 0.107 0.484 View mutations
89 P 19 0 19 0.011 0.398 View mutations
90 D 19 0 19 0.000 0.462 View mutations
91 S 6 13 19 0.672 0.576 View mutations
92 L 19 0 19 0.000 0.503 View mutations
93 E 18 1 19 0.037 0.544 View mutations
94 N 19 0 19 0.002 0.411 View mutations
95 I 2 17 19 0.876 0.448 View mutations
96 P 19 0 19 0.039 0.768 View mutations
97 E 19 0 19 0.000 0.561 View mutations
98 K 18 1 19 0.168 0.391 View mutations
99 W 6 13 19 0.661 0.508 View mutations
100 T 7 12 19 0.567 0.404 View mutations