P61586 (RHOA)

Overview
Predicted structure (AF):
AF-P61586-F1-model_v4
Uniprot entry:
P61586
Gene:
RHOA
Protein length:
193 residues
Mutations found:
3666
Benign based on D2Deep prediction:
2470 out of 3666 mutations
Pathogenic based on D2Deep prediction:
1196 out of 3666 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3666 mutations across 193 unique positions. There are 2470 benign and 1196 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 P 19 0 19 0.001 0.352 View mutations
102 E 4 15 19 0.750 0.614 View mutations
103 V 5 14 19 0.777 0.453 View mutations
104 K 11 8 19 0.471 0.500 View mutations
105 H 2 17 19 0.865 0.458 View mutations
106 F 17 2 19 0.131 0.446 View mutations
107 C 19 0 19 0.000 0.389 View mutations
108 P 15 4 19 0.250 0.489 View mutations
109 N 19 0 19 0.000 0.517 View mutations
110 V 19 0 19 0.000 0.487 View mutations
111 P 15 4 19 0.204 0.487 View mutations
112 I 18 1 19 0.071 0.519 View mutations
113 I 19 0 19 0.017 0.434 View mutations
114 L 2 17 19 0.877 0.667 View mutations
115 V 4 15 19 0.803 0.549 View mutations
116 G 8 11 19 0.602 0.436 View mutations
117 N 5 14 19 0.743 0.518 View mutations
118 K 12 7 19 0.432 0.492 View mutations
119 K 19 0 19 0.004 0.614 View mutations
120 D 17 2 19 0.151 0.320 View mutations
121 L 8 11 19 0.531 0.519 View mutations
122 R 19 0 19 0.022 0.421 View mutations
123 N 19 0 19 0.073 0.700 View mutations
124 D 18 1 19 0.147 0.706 View mutations
125 E 19 0 19 0.018 0.839 View mutations