P63000-2 (RAC1)

Overview
Predicted structure (AF):
AF-P63000-2-F1-model_v4
Uniprot entry:
P63000-2
Gene:
RAC1
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
2097 out of 4008 mutations
Pathogenic based on D2Deep prediction:
1911 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 2097 benign and 1911 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 F 17 2 19 0.158 0.468 View mutations
102 S 3 16 19 0.826 0.458 View mutations
103 L 12 7 19 0.401 0.441 View mutations
104 V 3 16 19 0.867 0.389 View mutations
105 S 1 18 19 0.927 0.378 View mutations
106 P 19 0 19 0.090 0.570 View mutations
107 A 19 0 19 0.002 0.571 View mutations
108 S 0 19 19 0.995 0.669 View mutations
109 F 18 1 19 0.108 0.551 View mutations
110 E 19 0 19 0.000 0.618 View mutations
111 N 2 17 19 0.900 0.510 View mutations
112 V 9 10 19 0.476 0.435 View mutations
113 R 19 0 19 0.007 0.857 View mutations
114 A 13 6 19 0.297 0.557 View mutations
115 K 2 17 19 0.856 0.448 View mutations
116 W 11 8 19 0.494 0.495 View mutations
117 Y 10 9 19 0.602 0.488 View mutations
118 P 19 0 19 0.039 0.435 View mutations
119 E 3 16 19 0.793 0.635 View mutations
120 V 17 2 19 0.113 0.397 View mutations
121 R 15 4 19 0.233 0.616 View mutations
122 H 16 3 19 0.127 0.399 View mutations
123 H 8 11 19 0.613 0.504 View mutations
124 C 15 4 19 0.265 0.478 View mutations
125 P 3 16 19 0.770 0.525 View mutations