Q01130 (SRSF2)

Overview
Predicted structure (AF):
AF-Q01130-F1-model_v4
Uniprot entry:
Q01130
Gene:
SRSF2
Protein length:
221 residues
Mutations found:
4198
Benign based on D2Deep prediction:
2468 out of 4198 mutations
Pathogenic based on D2Deep prediction:
1730 out of 4198 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4198 mutations across 221 unique positions. There are 2468 benign and 1730 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 D 0 19 19 1.000 0.731 View mutations
77 G 1 18 19 0.948 0.702 View mutations
78 A 0 19 19 1.000 0.670 View mutations
79 V 3 16 19 0.858 0.543 View mutations
80 L 0 19 19 1.000 0.702 View mutations
81 D 0 19 19 1.000 0.721 View mutations
82 G 0 19 19 0.996 0.778 View mutations
83 R 0 19 19 1.000 0.653 View mutations
84 E 1 18 19 0.937 0.681 View mutations
85 L 1 18 19 0.950 0.721 View mutations
86 R 3 16 19 0.754 0.646 View mutations
87 V 9 10 19 0.534 0.509 View mutations
88 Q 7 12 19 0.573 0.541 View mutations
89 M 18 1 19 0.090 0.343 View mutations
90 A 19 0 19 0.004 0.330 View mutations
91 R 19 0 19 0.000 0.487 View mutations
92 Y 19 0 19 0.012 0.480 View mutations
93 G 19 0 19 0.013 0.360 View mutations
94 R 19 0 19 0.014 0.523 View mutations
95 P 1 18 19 0.829 0.373 View mutations
96 P 17 2 19 0.140 0.565 View mutations
97 D 19 0 19 0.009 0.607 View mutations
98 S 19 0 19 0.016 0.673 View mutations
99 H 13 6 19 0.306 0.589 View mutations
100 H 12 7 19 0.373 0.568 View mutations