Q01130 (SRSF2)

Overview
Predicted structure (AF):
AF-Q01130-F1-model_v4
Uniprot entry:
Q01130
Gene:
SRSF2
Protein length:
221 residues
Mutations found:
4198
Benign based on D2Deep prediction:
2468 out of 4198 mutations
Pathogenic based on D2Deep prediction:
1730 out of 4198 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4198 mutations across 221 unique positions. There are 2468 benign and 1730 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 R 8 11 19 0.624 0.424 View mutations
127 R 7 12 19 0.606 0.376 View mutations
128 S 0 19 19 0.996 0.085 View mutations
129 R 5 14 19 0.708 0.292 View mutations
130 S 2 17 19 0.871 0.167 View mutations
131 R 2 17 19 0.874 0.158 View mutations
132 S 1 18 19 0.961 0.148 View mutations
133 R 12 7 19 0.434 0.594 View mutations
134 S 1 18 19 0.951 0.145 View mutations
135 R 12 7 19 0.377 0.603 View mutations
136 S 1 18 19 0.896 0.126 View mutations
137 R 9 10 19 0.477 0.468 View mutations
138 S 11 8 19 0.421 0.543 View mutations
139 R 19 0 19 0.046 0.918 View mutations
140 S 19 0 19 0.096 0.901 View mutations
141 R 19 0 19 0.016 0.928 View mutations
142 S 19 0 19 0.010 0.912 View mutations
143 R 19 0 19 0.035 0.895 View mutations
144 Y 19 0 19 0.033 0.931 View mutations
145 S 19 0 19 0.011 0.898 View mutations
146 R 19 0 19 0.000 0.932 View mutations
147 S 19 0 19 0.003 0.944 View mutations
148 K 19 0 19 0.000 0.919 View mutations
149 S 19 0 19 0.056 0.917 View mutations
150 R 19 0 19 0.015 0.944 View mutations