O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 T 17 2 19 0.146 0.577 View mutations
252 F 12 7 19 0.379 0.441 View mutations
253 I 5 14 19 0.775 0.422 View mutations
254 T 17 2 19 0.115 0.445 View mutations
255 D 18 1 19 0.082 0.575 View mutations
256 N 13 6 19 0.247 0.506 View mutations
257 S 11 8 19 0.466 0.475 View mutations
258 L 19 0 19 0.080 0.509 View mutations
259 V 18 1 19 0.114 0.499 View mutations
260 A 19 0 19 0.000 0.379 View mutations
261 A 5 14 19 0.768 0.517 View mutations
262 G 0 19 19 1.000 0.440 View mutations
263 H 16 3 19 0.218 0.407 View mutations
264 D 15 4 19 0.218 0.494 View mutations
265 C 17 2 19 0.063 0.412 View mutations
266 F 19 0 19 0.006 0.530 View mutations
267 P 4 15 19 0.794 0.446 View mutations
268 V 16 3 19 0.152 0.502 View mutations
269 L 9 10 19 0.568 0.440 View mutations
270 F 5 14 19 0.630 0.423 View mutations
271 T 17 2 19 0.094 0.662 View mutations
272 Y 19 0 19 0.013 0.755 View mutations
273 D 19 0 19 0.001 0.939 View mutations
274 A 19 0 19 0.001 0.874 View mutations
275 A 19 0 19 0.001 0.839 View mutations