O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 C 19 0 19 0.002 0.392 View mutations
102 V 13 6 19 0.376 0.404 View mutations
103 R 10 9 19 0.454 0.492 View mutations
104 W 2 17 19 0.874 0.623 View mutations
105 A 3 16 19 0.861 0.599 View mutations
106 P 0 19 19 0.972 0.768 View mutations
107 N 18 1 19 0.070 0.499 View mutations
108 E 3 16 19 0.833 0.575 View mutations
109 N 19 0 19 0.013 0.312 View mutations
110 K 16 3 19 0.181 0.319 View mutations
111 F 5 14 19 0.771 0.584 View mutations
112 A 1 18 19 0.956 0.791 View mutations
113 V 17 2 19 0.162 0.255 View mutations
114 G 13 6 19 0.309 0.414 View mutations
115 S 1 18 19 0.938 0.670 View mutations
116 G 17 2 19 0.134 0.320 View mutations
117 S 3 16 19 0.860 0.582 View mutations
118 R 17 2 19 0.109 0.421 View mutations
119 V 13 6 19 0.366 0.447 View mutations
120 I 8 11 19 0.565 0.536 View mutations
121 S 0 19 19 0.986 0.789 View mutations
122 I 7 12 19 0.644 0.577 View mutations
123 C 0 19 19 0.994 0.779 View mutations
124 Y 1 18 19 0.925 0.734 View mutations
125 F 1 18 19 0.960 0.712 View mutations