O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 L 19 0 19 0.000 0.377 View mutations
102 F 11 8 19 0.424 0.463 View mutations
103 R 11 8 19 0.484 0.487 View mutations
104 T 4 15 19 0.755 0.454 View mutations
105 F 0 19 19 0.999 0.657 View mutations
106 L 1 18 19 0.959 0.818 View mutations
107 K 13 6 19 0.306 0.411 View mutations
108 Q 2 17 19 0.869 0.594 View mutations
109 E 2 17 19 0.900 0.619 View mutations
110 G 12 7 19 0.423 0.490 View mutations
111 C 6 13 19 0.597 0.547 View mutations
112 A 8 11 19 0.578 0.524 View mutations
113 D 9 10 19 0.495 0.514 View mutations
114 L 8 11 19 0.543 0.521 View mutations
115 L 0 19 19 0.974 0.798 View mutations
116 D 15 4 19 0.272 0.295 View mutations
117 F 0 19 19 0.999 0.865 View mutations
118 W 0 19 19 1.000 0.842 View mutations
119 F 7 12 19 0.673 0.595 View mutations
120 A 1 18 19 0.902 0.915 View mutations
121 C 0 19 19 1.000 0.903 View mutations
122 T 1 18 19 0.890 0.803 View mutations
123 G 0 19 19 1.000 0.825 View mutations
124 F 0 19 19 0.999 0.775 View mutations
125 R 0 19 19 1.000 0.726 View mutations