O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
751 H 19 0 19 0.041 0.900 View mutations
752 V 18 1 19 0.041 0.811 View mutations
753 V 19 0 19 0.000 0.802 View mutations
754 P 19 0 19 0.015 0.828 View mutations
755 A 15 4 19 0.266 0.684 View mutations
756 V 19 0 19 0.066 0.858 View mutations
757 S 19 0 19 0.000 0.871 View mutations
758 D 19 0 19 0.000 0.804 View mutations
759 M 19 0 19 0.002 0.883 View mutations
760 E 19 0 19 0.016 0.811 View mutations
761 L 19 0 19 0.003 0.782 View mutations
762 S 19 0 19 0.000 0.870 View mutations
763 E 19 0 19 0.000 0.844 View mutations
764 T 17 2 19 0.126 0.802 View mutations
765 E 18 1 19 0.101 0.824 View mutations
766 T 19 0 19 0.002 0.892 View mutations
767 R 19 0 19 0.003 0.856 View mutations
768 S 18 1 19 0.094 0.801 View mutations
769 Q 15 4 19 0.204 0.691 View mutations
770 R 19 0 19 0.142 0.812 View mutations
771 K 7 12 19 0.565 0.390 View mutations
772 V 19 0 19 0.017 0.886 View mutations
773 G 16 3 19 0.261 0.767 View mutations
774 G 8 11 19 0.553 0.422 View mutations
775 G 16 3 19 0.186 0.767 View mutations