O43543 (XRCC2)

Overview
Predicted structure (AF):
AF-O43543-F1-model_v4
Uniprot entry:
O43543
Gene:
XRCC2
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
2575 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2744 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5319 mutations across 280 unique positions. There are 2575 benign and 2744 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 S 19 0 19 0.012 0.608 View mutations
102 Q 17 2 19 0.138 0.570 View mutations
103 S 4 15 19 0.735 0.340 View mutations
104 S 5 14 19 0.743 0.381 View mutations
105 E 0 19 19 0.966 0.515 View mutations
106 E 5 14 19 0.599 0.414 View mutations
107 I 18 1 19 0.063 0.574 View mutations
108 I 5 14 19 0.748 0.520 View mutations
109 K 18 1 19 0.110 0.414 View mutations
110 Y 18 1 19 0.033 0.584 View mutations
111 C 8 11 19 0.595 0.507 View mutations
112 L 1 18 19 0.945 0.614 View mutations
113 G 19 0 19 0.017 0.430 View mutations
114 R 16 3 19 0.192 0.437 View mutations
115 F 3 16 19 0.797 0.603 View mutations
116 F 11 8 19 0.467 0.499 View mutations
117 L 1 18 19 0.933 0.607 View mutations
118 V 15 4 19 0.249 0.443 View mutations
119 Y 15 4 19 0.269 0.465 View mutations
120 C 12 7 19 0.346 0.423 View mutations
121 S 6 13 19 0.699 0.546 View mutations
122 S 11 8 19 0.411 0.456 View mutations
123 S 0 19 19 0.914 0.739 View mutations
124 T 9 10 19 0.572 0.504 View mutations
125 H 1 18 19 0.965 0.673 View mutations