O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
426 Q 19 0 19 0.010 0.846 View mutations
427 N 19 0 19 0.121 0.882 View mutations
428 L 15 4 19 0.242 0.730 View mutations
429 A 19 0 19 0.001 0.885 View mutations
430 P 19 0 19 0.015 0.929 View mutations
431 G 19 0 19 0.001 0.802 View mutations
432 A 19 0 19 0.011 0.747 View mutations
433 R 19 0 19 0.000 0.679 View mutations
434 C 17 2 19 0.139 0.632 View mutations
435 G 19 0 19 0.000 0.585 View mutations
436 V 19 0 19 0.000 0.579 View mutations
437 C 18 1 19 0.108 0.635 View mutations
438 G 14 5 19 0.268 0.550 View mutations
439 D 14 5 19 0.229 0.564 View mutations
440 G 7 12 19 0.626 0.404 View mutations
441 T 11 8 19 0.474 0.520 View mutations
442 D 19 0 19 0.008 0.701 View mutations
443 V 16 3 19 0.180 0.604 View mutations
444 L 8 11 19 0.609 0.429 View mutations
445 R 19 0 19 0.029 0.612 View mutations
446 C 19 0 19 0.002 0.607 View mutations
447 T 19 0 19 0.001 0.647 View mutations
448 H 19 0 19 0.002 0.692 View mutations
449 C 0 19 19 0.999 0.322 View mutations
450 A 19 0 19 0.000 0.699 View mutations