O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 P 19 0 19 0.025 0.201 View mutations
102 K 18 1 19 0.152 0.383 View mutations
103 D 1 18 19 0.955 0.743 View mutations
104 V 0 19 19 0.985 0.807 View mutations
105 D 0 19 19 1.000 0.721 View mutations
106 L 3 16 19 0.841 0.623 View mutations
107 S 8 11 19 0.559 0.514 View mutations
108 Q 12 7 19 0.414 0.494 View mutations
109 P 14 5 19 0.239 0.452 View mutations
110 R 19 0 19 0.001 0.352 View mutations
111 K 15 4 19 0.174 0.483 View mutations
112 G 17 2 19 0.118 0.377 View mutations
113 R 19 0 19 0.001 0.454 View mutations
114 K 19 0 19 0.013 0.472 View mutations
115 P 17 2 19 0.162 0.462 View mutations
116 P 19 0 19 0.008 0.584 View mutations
117 A 13 6 19 0.347 0.500 View mutations
118 V 19 0 19 0.001 0.563 View mutations
119 P 19 0 19 0.015 0.592 View mutations
120 K 19 0 19 0.023 0.523 View mutations
121 A 17 2 19 0.158 0.595 View mutations
122 L 19 0 19 0.005 0.691 View mutations
123 V 14 5 19 0.284 0.509 View mutations
124 P 19 0 19 0.132 0.623 View mutations
125 P 13 6 19 0.331 0.501 View mutations