O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 K 17 2 19 0.135 0.610 View mutations
302 T 19 0 19 0.000 0.459 View mutations
303 V 5 14 19 0.718 0.444 View mutations
304 E 1 18 19 0.936 0.653 View mutations
305 A 19 0 19 0.001 0.366 View mutations
306 E 0 19 19 0.981 0.802 View mutations
307 A 5 14 19 0.703 0.681 View mutations
308 A 4 15 19 0.732 0.707 View mutations
309 H 12 7 19 0.399 0.392 View mutations
310 G 1 18 19 0.914 0.858 View mutations
311 T 2 17 19 0.852 0.780 View mutations
312 V 19 0 19 0.006 0.274 View mutations
313 T 19 0 19 0.002 0.361 View mutations
314 R 3 16 19 0.881 0.539 View mutations
315 H 2 17 19 0.908 0.585 View mutations
316 Y 16 3 19 0.163 0.472 View mutations
317 R 19 0 19 0.051 0.561 View mutations
318 M 19 0 19 0.033 0.632 View mutations
319 Y 1 18 19 0.915 0.505 View mutations
320 Q 17 2 19 0.161 0.397 View mutations
321 K 19 0 19 0.003 0.728 View mutations
322 G 0 19 19 0.982 0.569 View mutations
323 Q 18 1 19 0.064 0.685 View mutations
324 E 5 14 19 0.767 0.410 View mutations
325 T 0 19 19 1.000 0.721 View mutations