O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 N 19 0 19 0.004 0.387 View mutations
102 I 10 9 19 0.453 0.497 View mutations
103 L 2 17 19 0.878 0.661 View mutations
104 G 1 18 19 0.936 0.611 View mutations
105 G 0 19 19 1.000 0.787 View mutations
106 T 1 18 19 0.921 0.618 View mutations
107 V 18 1 19 0.125 0.340 View mutations
108 F 0 19 19 1.000 0.683 View mutations
109 R 2 17 19 0.873 0.658 View mutations
110 E 18 1 19 0.056 0.490 View mutations
111 A 8 11 19 0.567 0.510 View mutations
112 I 3 16 19 0.829 0.544 View mutations
113 I 19 0 19 0.001 0.395 View mutations
114 C 19 0 19 0.017 0.475 View mutations
115 K 19 0 19 0.005 0.647 View mutations
116 N 18 1 19 0.074 0.484 View mutations
117 I 1 18 19 0.945 0.546 View mutations
118 P 15 4 19 0.319 0.417 View mutations
119 R 15 4 19 0.221 0.443 View mutations
120 L 19 0 19 0.004 0.464 View mutations
121 V 1 18 19 0.921 0.575 View mutations
122 S 19 0 19 0.005 0.566 View mutations
123 G 11 8 19 0.491 0.460 View mutations
124 W 1 18 19 0.948 0.586 View mutations
125 V 14 5 19 0.218 0.479 View mutations