P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 F 0 19 19 1.000 0.801 View mutations
352 K 1 18 19 0.948 0.670 View mutations
353 N 0 19 19 1.000 0.787 View mutations
354 E 0 19 19 1.000 0.846 View mutations
355 M 0 19 19 1.000 0.789 View mutations
356 Q 6 13 19 0.680 0.586 View mutations
357 V 0 19 19 1.000 0.901 View mutations
358 L 0 19 19 1.000 0.822 View mutations
359 R 0 19 19 1.000 0.739 View mutations
360 K 3 16 19 0.851 0.719 View mutations
361 T 0 19 19 1.000 1.000 View mutations
362 R 0 19 19 1.000 0.934 View mutations
363 H 0 19 19 1.000 0.942 View mutations
364 V 0 19 19 1.000 0.920 View mutations
365 N 0 19 19 1.000 0.938 View mutations
366 I 0 19 19 1.000 0.859 View mutations
367 L 0 19 19 0.973 0.822 View mutations
368 L 0 19 19 1.000 0.831 View mutations
369 F 0 19 19 1.000 0.795 View mutations
370 M 4 15 19 0.769 0.691 View mutations
371 G 0 19 19 0.999 0.744 View mutations
372 F 10 9 19 0.497 0.494 View mutations
373 M 1 18 19 0.941 0.557 View mutations
374 T 9 10 19 0.605 0.507 View mutations
375 R 4 15 19 0.760 0.535 View mutations