P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
376 P 15 4 19 0.212 0.440 View mutations
377 G 13 6 19 0.326 0.470 View mutations
378 F 1 18 19 0.951 0.668 View mutations
379 A 0 19 19 1.000 0.690 View mutations
380 I 0 19 19 1.000 0.866 View mutations
381 I 1 18 19 0.936 0.787 View mutations
382 T 0 19 19 1.000 0.882 View mutations
383 Q 0 19 19 1.000 0.924 View mutations
384 W 2 17 19 0.913 0.786 View mutations
385 C 0 19 19 1.000 0.936 View mutations
386 E 1 18 19 0.949 0.849 View mutations
387 G 0 19 19 1.000 0.983 View mutations
388 S 2 17 19 0.865 0.688 View mutations
389 S 0 19 19 1.000 0.860 View mutations
390 L 4 15 19 0.805 0.713 View mutations
391 Y 2 17 19 0.882 0.722 View mutations
392 H 8 11 19 0.529 0.526 View mutations
393 H 0 19 19 0.983 0.721 View mutations
394 L 5 14 19 0.747 0.641 View mutations
395 H 19 0 19 0.010 0.289 View mutations
396 V 19 0 19 0.001 0.347 View mutations
397 A 15 4 19 0.206 0.457 View mutations
398 D 5 14 19 0.681 0.554 View mutations
399 T 18 1 19 0.039 0.423 View mutations
400 R 6 13 19 0.672 0.519 View mutations