P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
401 F 1 18 19 0.938 0.571 View mutations
402 D 19 0 19 0.012 0.492 View mutations
403 M 15 4 19 0.229 0.465 View mutations
404 V 8 11 19 0.593 0.501 View mutations
405 Q 18 1 19 0.077 0.451 View mutations
406 L 19 0 19 0.008 0.320 View mutations
407 I 12 7 19 0.382 0.459 View mutations
408 D 0 19 19 0.979 0.688 View mutations
409 V 11 8 19 0.466 0.476 View mutations
410 A 9 10 19 0.536 0.511 View mutations
411 R 0 19 19 1.000 0.699 View mutations
412 Q 0 19 19 1.000 0.860 View mutations
413 T 0 19 19 1.000 0.844 View mutations
414 A 0 19 19 0.999 0.831 View mutations
415 Q 1 18 19 0.959 0.717 View mutations
416 G 0 19 19 1.000 0.864 View mutations
417 M 0 19 19 1.000 0.776 View mutations
418 D 2 17 19 0.841 0.671 View mutations
419 Y 0 19 19 0.999 0.813 View mutations
420 L 0 19 19 1.000 0.793 View mutations
421 H 0 19 19 0.997 0.776 View mutations
422 A 13 6 19 0.328 0.417 View mutations
423 K 0 19 19 0.999 0.740 View mutations
424 N 2 17 19 0.885 0.666 View mutations
425 I 1 18 19 0.937 0.766 View mutations