P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
426 I 5 14 19 0.724 0.630 View mutations
427 H 0 19 19 1.000 0.733 View mutations
428 R 0 19 19 1.000 0.707 View mutations
429 D 0 19 19 1.000 0.657 View mutations
430 L 1 18 19 0.947 0.674 View mutations
431 K 0 19 19 1.000 0.681 View mutations
432 S 1 18 19 0.968 0.672 View mutations
433 N 3 16 19 0.820 0.560 View mutations
434 N 0 19 19 1.000 0.679 View mutations
435 I 6 13 19 0.682 0.633 View mutations
436 F 7 12 19 0.585 0.545 View mutations
437 L 15 4 19 0.205 0.381 View mutations
438 H 1 18 19 0.971 0.679 View mutations
439 E 15 4 19 0.228 0.391 View mutations
440 G 1 18 19 0.929 0.684 View mutations
441 L 0 19 19 0.967 0.698 View mutations
442 T 13 6 19 0.264 0.386 View mutations
443 V 8 11 19 0.592 0.556 View mutations
444 K 0 19 19 1.000 0.876 View mutations
445 I 0 19 19 0.991 0.832 View mutations
446 G 13 6 19 0.355 0.353 View mutations
447 D 0 19 19 1.000 0.921 View mutations
448 F 0 19 19 1.000 0.869 View mutations
449 G 0 19 19 1.000 0.935 View mutations
450 L 0 19 19 1.000 0.877 View mutations