P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
451 A 0 19 19 0.996 0.882 View mutations
452 T 0 19 19 1.000 0.842 View mutations
453 V 3 16 19 0.848 0.705 View mutations
454 K 2 17 19 0.875 0.717 View mutations
455 T 12 7 19 0.404 0.444 View mutations
456 R 1 18 19 0.953 0.640 View mutations
457 W 0 19 19 1.000 0.710 View mutations
458 S 0 19 19 0.995 0.708 View mutations
459 G 1 18 19 0.913 0.681 View mutations
460 A 19 0 19 0.025 0.362 View mutations
461 Q 18 1 19 0.058 0.497 View mutations
462 P 15 4 19 0.202 0.479 View mutations
463 L 18 1 19 0.045 0.448 View mutations
464 E 18 1 19 0.046 0.432 View mutations
465 Q 0 19 19 0.995 0.622 View mutations
466 P 4 15 19 0.791 0.591 View mutations
467 S 1 18 19 0.940 0.631 View mutations
468 G 0 19 19 1.000 0.674 View mutations
469 S 0 19 19 1.000 0.693 View mutations
470 V 1 18 19 0.948 0.663 View mutations
471 L 0 19 19 1.000 0.707 View mutations
472 W 0 19 19 1.000 0.754 View mutations
473 M 12 7 19 0.341 0.422 View mutations
474 A 3 16 19 0.816 0.674 View mutations
475 A 1 18 19 0.942 0.715 View mutations