P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
476 E 1 18 19 0.963 0.736 View mutations
477 V 1 18 19 0.951 0.724 View mutations
478 I 8 11 19 0.583 0.538 View mutations
479 R 0 19 19 1.000 0.690 View mutations
480 M 0 19 19 0.998 0.668 View mutations
481 Q 1 18 19 0.948 0.589 View mutations
482 D 1 18 19 0.958 0.579 View mutations
483 P 14 5 19 0.278 0.395 View mutations
484 N 10 9 19 0.442 0.493 View mutations
485 P 17 2 19 0.117 0.246 View mutations
486 Y 1 18 19 0.967 0.683 View mutations
487 S 1 18 19 0.947 0.737 View mutations
488 F 5 14 19 0.692 0.616 View mutations
489 Q 10 9 19 0.535 0.485 View mutations
490 S 7 12 19 0.643 0.587 View mutations
491 D 0 19 19 1.000 0.800 View mutations
492 V 0 19 19 0.997 0.746 View mutations
493 Y 0 19 19 1.000 0.667 View mutations
494 A 6 13 19 0.695 0.566 View mutations
495 Y 0 19 19 0.999 0.676 View mutations
496 G 3 16 19 0.862 0.654 View mutations
497 V 4 15 19 0.802 0.607 View mutations
498 V 0 19 19 1.000 0.721 View mutations
499 L 0 19 19 0.999 0.577 View mutations
500 Y 2 17 19 0.899 0.521 View mutations