P10415 (BCL2)

Overview
Predicted structure (AF):
AF-P10415-F1-model_v4
Uniprot entry:
P10415
Gene:
BCL2
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
3113 out of 4540 mutations
Pathogenic based on D2Deep prediction:
1427 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4540 mutations across 239 unique positions. There are 3113 benign and 1427 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 F 7 12 19 0.587 0.592 View mutations
152 E 1 18 19 0.815 0.858 View mutations
153 F 11 8 19 0.421 0.429 View mutations
154 G 10 9 19 0.517 0.480 View mutations
155 G 0 19 19 0.981 0.939 View mutations
156 V 7 12 19 0.633 0.620 View mutations
157 M 7 12 19 0.662 0.622 View mutations
158 C 0 19 19 0.974 0.940 View mutations
159 V 3 16 19 0.882 0.819 View mutations
160 E 1 18 19 0.938 0.944 View mutations
161 S 3 16 19 0.797 0.813 View mutations
162 V 0 19 19 0.999 0.884 View mutations
163 N 1 18 19 0.945 0.808 View mutations
164 R 2 17 19 0.841 0.742 View mutations
165 E 10 9 19 0.491 0.477 View mutations
166 M 2 17 19 0.808 0.782 View mutations
167 S 16 3 19 0.146 0.258 View mutations
168 P 13 6 19 0.306 0.365 View mutations
169 L 19 0 19 0.016 0.093 View mutations
170 V 14 5 19 0.210 0.314 View mutations
171 D 16 3 19 0.317 0.296 View mutations
172 N 19 0 19 0.036 0.304 View mutations
173 I 19 0 19 0.002 0.140 View mutations
174 A 19 0 19 0.005 0.224 View mutations
175 L 19 0 19 0.023 0.423 View mutations